image Our Team
  Our Team
image Faculty
  Post-Doctoral Researchers
  Doctoral Students
  Research Staff
  Administrative Staff
   
image
Ian Lipkin

W. Ian Lipkin, mD

John Snow Professor of Epidemiology, Professor of Neurology and Pathology

Mailman School of Public Health and College of Physicians and Surgeons, Columbia University

Phone: 212.342.9033
Fax: 212.342.9044
Email: wil2001@columbia.edu

 
Education & Training
  • Sarah Lawrence College, Bronxville, New York, BA, 1974
  • Rush Medical College, Chicago, Illinois, M.D., 1978
  • Clinical Clerk, Institute of Neurology, Queen Square, London, UK, 1977-78
  • Intern in Medicine, Presbyterian Hospital, University of Pittsburgh, Pittsburgh, PA, 1978-79
  • Resident in Medicine, University of Washington, Seattle, WA, 1979-81
  • Resident in Neurology, University of California, San Francisco, CA, 1981-84
  • Postdoctoral Fellow (Michael Oldstone & Floyd Bloom), Scripps Research Institute, La Jolla, CA, 1984-90
  • Asst. Professor (1990-93), Assoc. Professor (1993-96), Professor (1996-02), Neurology; Anatomy & Neurobiology; Microbiology & Molecular Genetics, University of California Irvine, Irvine, CA, 1990-02
  • Sabbatical Professor, Institut fur Virologie und Immunbiologie, Universitut Wurzburg, Germany, 1996-97
  • Adjunct Professor, Neuropharmacology, The Scripps Research Institute, La Jolla, CA, 1996-02
  • Louise Turner Arnold Professor of Neuroscience, University of California Irvine, Irvine, CA, 2000-02
  • Jerome L. and Dawn Greene Professor of Epidemiology; Director, Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health; Professor of Neurology and Pathology, College of Physicians & Surgeons; Columbia University, New York, NY, 2002-07
  • Principal Investigator and Scientific Director, Northeast Biodefense Center, Region II NIAID Regional Center of Excellence for Biodefense and Emerging Infectious Diseases, 2003-present
  • Dalldorf Research Physician, Wadsworth Center, New York State Dept of Health, 2003-present
  • Professor of Epidemiology, Neurology and Pathology; Director, Center for Infection and Immunity; Mailman School of Public Health and College of Physicians & Surgeons; Columbia University, New York, NY, 2007- present
  • Director, WHO Collaborating Centre for Diagnostics, Surveillance, and Immunotherapeutics for Emerging Infectious and Zoonotic Diseases, 2008-present

Bio

W. Ian Lipkin, M.D. is the Director of the Center for Infection and Immunity, and Professor of Epidemiology, Neurology and Pathology in the Mailman School of Public Health and College of Physicians and Surgeons at Columbia University. A physician-scientist, Lipkin is internationally recognized for his work with West Nile virus and SARS, as well as advancing pathogen discovery techniques by developing a staged strategy using techniques pioneered in his lab. These molecular biological methods, including MassTag-PCR, the GreeneChip diagnostic, and High Throughput Sequencing, are a major step towards identifying and studying new viral pathogens that emerge locally throughout the globe. A major node in a global network of investigators working to address the challenges of pathogen surveillance and discovery, Dr. Lipkin has trained over 30 internationally based scientists in these state-of-the art diagnostic techniques.

Scientific interests

Lipkin is the Director of the Northeast Biodefense Center, the Regional Center of Excellence in Biodefense and Emerging Infectious Diseases comprising 28 private and public academic and public health institutions in New York, New Jersey and Connecticut. Within this consortium, his research focuses on pathogen discovery, using unexplained hemorrhagic fever, febrile illness, encephalitis, and meningoencephalitis as targets. He is the Principal Investigator of the Autism Birth Cohort, a unique international program that investigates the epidemiology and basis of neurodevelopmental disorders through analyses of a prospective birth cohort of 100,000 children and their parents. Lipkin also directs the World Health Organization Collaborating Centre for Diagnostics in Zoonotic and Emerging Infectious Diseases. In 1989, Lipkin was the first to identify a microbe (Bornavirus) using purely molecular tools. In 1999, Lipkin led the team that identified the West Nile virus in brains of encephalitis victims in New York State. In April of 2003, he sequenced a portion of the SARS virus directly from lung tissue, established a sensitive assay for infection, and hand carried 10,000 test kits to Beijing at the height of the outbreak. He became ill shortly after returning to the US and was quarantined. As the first foreign consultant to gain the confidence of the Ministry of Science and Technology and the Chinese Academy of Science he was named Special Advisor to China for Research and International Cooperation in Infectious Diseases was instrumental in promoting disclosure and outside collaborations in infectious disease research and public health management. He is Honorary Director of the Beijing Infectious Disease Center, Chair of the Scientific Advisory Board of the Institut Pasteur de Shanghai and serves on boards of the Australian Biosecurity Cooperative Research Centre for Emerging Infectious Disease, the Guangzhou Institute for Biomedicine and Health, the Consortium for Conservation Medicine, Tetragenetics, and 454 Life Sciences Corporation.

Service activities

  • Director, Center for Infection and Immunity
  • Principal Investigator and Scientific Director, Northeast Biodefense Center
  • Principal Investigator, Autism Birth Cohort
  • Director, WHO Collaborating Centre for Diagnostics in Zoonotic and Emerging Infectious Diseases
SELECTED Publications

  • Briese T, Paweska JT, McMullan LK, Hutchison SK, Street C, Palacios G, Khristova ML, Weyer J, Swanepoel R, Egholm E, Nichol ST, Lipkin WI (2009) Genetic Detection and Characterization of Lujo Virus, a New Hemorrhagic Fever–Associated Arenavirus from Southern Africa. PLoS Pathog 4(5): e1000455. doi:10.1371/journal.ppat.1000455
  • Cowled C, Palacios G, Melville L, Weir R, Walsh S, Davis S Gubala A, Lipkin WI, Briese T, Boyle D (2009) Genetic and epidemiological characterization of Stretch Lagoon orbivirus, a new orbivirus species isolated from Culex and Aedes mosquitoes in northern Australia. J Gen Virol 90, 1433-1439; DOI 10.1099/vir.0.010074-0
  • Siemetzki U, Ashok MS, Briese T, Lipkin WI (2009) Identification of RNA instability in Borna disease virus. Virus Res, doi:10.1016/j.virusres.2009.03.016
  • Paweska,JT, Sewlall NH, Ksiazek TG, Blumberg LH, Hale MJ, Lipkin WI, Weyer J, Nichol ST, Rollin PE, McMullan LK, Paddock CD, Briese T, Mnyaluza J, Dinh, Mukonka V, Ching P, Duse,A, de Jong G, Cohen C, Ikalafeng B, Mugero C, Asamugha C, Malotle MM, Nteo DM, Misiani E, Swanepoel R, Zaki SR (2009) Nosocomial outbreak of disease in southern Africa caused by a novel arenavirus. Emerg Infect Dis, In Press.
  • Lipkin WI (2009) Microbe hunting in the 21st century. Proc Natl Acad Sci USA Jan 6;106(1):6-7.
  • Honkavuori KS, Shivaprasad HL, Williams BL, Quan PL, Hornig M, Street C, Palacios G, Hutchison SK, Franca M, Egholm M, Briese T, Lipkin WI (2008) Novel borna virus in psittacine birds with proventricular dilatation disease. Emerg Infect Dis. 2008 Dec;14(12):1883-6.
  • De Miranda J, Yaddanapudi K, Hornig M, Lipkin WI. (2008) Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5. FASEB 2008 Nov 26. [Epub ahead of print]
  • Towner JS, Sealy TK, Khristova ML, Albariño CG, Conlan S, Reeder SA, Quan PL, Lipkin WI, Downing R, Tappero JW, Okware S, Lutwama J, Bakamutumaho B, Kayiwa J, Comer JA, Rollin PE, Ksiazek TG, Nichol ST. (2008) Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog 2008 Nov; 4(11):e1000212. Epub 2008 Nov 21.
  • Tokarz R, Kapoor V, Samuel JE, Bouyer DH, Briese T, Lipkin WI (2008) Detection of Tick-Borne Pathogens by MassTag Polymerase Chain Reaction. Vector Borne Zoonotic Dis Sep 18. [Epub ahead of print]
  • Briese T, Renwick N, Venter M, Jarman RG, Ghosh D, Kundgen S, Shrestha SK, Hoegh AM, Casas I, Adjogoua EV, Akoua-Koffi C, Myint KS, Williams DT, Chidlow G, van den Berg, Calvo C, Koch O, Palacios G, Kapoor V, Villari J, KV, Harnett G , Smith D, Mackenzie JS, Ellerbrok H, Schweiger B, Schunning K, Chadha MS, Leendertz FH, Mishra AC, Gibbons RV, Holmes EC, Lipkin WI (2008) Global distribution of a novel rhinovirus genotype. Emerg Infect Dis, 2008 Jun; 14(6):944-7.
  • Palacios G, Hui J, Quan PL, Kalkstein A, Honkavuori KS, Bussetti AV, Conlan S, Evans J, Chen YP, vanEngelsdorp D, Efrat H, Pettis J, Cox-Foster D, Holmes EC, Briese T, Lipkin WI. Genetic analysis of Israel Acute Paralysis Virus: distinct clusters are circulating into the United States J Virol, In Press.
  • Dominguez S, Briese T, Quan P-L, Palacios G, Renwick N, Hui J, Villari J, Kapoor V, Tokarz R, Glod MP, Anderson MS, Robinson CC, Holmes KV Jabado OJ, Lipkin WI. MassTag PCR of respiratory pathogens in pediatric nasopharyngeal washes negative by conventional diagnostic testing shows a high prevalence of viruses belonging to a newly recognized picornavirus clade. J Clin Virol. 2008 Oct;43(2):219-22.
  • Tokarz R, Fallon B, Lipkin WI. Co-infection of Ixodes scapularis and Demacentor variabilis with Borrelia burgdorferi and two species of pathogenic Bartonella in areas endemic for tick-borne diseases. Submitted.
  • Hornig M, Briese T, Buie T, Bauman M, Lauwers G, Siemetzki U, Hummel, K, Rota P, Bellini W, O'Leary J, Sheils O, Alden E, Pickering L, Lipkin WI. Lack of Association between Mealses Virus Vaccine and Autism with Enteropathy: A Case-control study. PLoS ONE. 2008 Sep 4;3(9):e3140.
  • Click here to see more publications.

 
images
footer
Google Map